Deadline for applications: 13th August 2025 As part of the project "Assessing and controlling seizure-modulating fluctuations (ACORN)", we are excited to recruit a motivated individual with research experience in a relevant subject area to work with us on this exciting project at the CNNP Lab. The aim of ACORN is to understand the role of biological rhythms (chronobiology) in epilepsy and develop time-adaptive therapies. This project is funded by UKRI and is a collaborative project that spans multiple continents. You will contribute to the development of new chronobiological analytics on existing data, design experiments to collect novel chronobiological data, engage with a wide network of stakeholders, and explore new avenues for medical applications. For ongoing work and publications on this project, please see our website: www.cnnp-lab.com. This is a 12-months position initially and is expected to be held full time and in person. As an UKRI-FLF funded role, the successful applicant may be eligible for the Endorsed Funder Route of the Global Talent Visa. We can provide an interest free loan scheme to support applicants who need to apply for a visa. Please contact Prof Yujiang Wang yujiang.wang@newcastle.ac.uk for specific questions. To apply, please complete an online application and upload a plain text copy of your CV (2 pages) and covering letter (1 page) only. In your covering letter, you should evidence how you meet or exceed the essential and desirable requirements for the role. Please note, any other ‘Additional Document’ you upload may not be received by the reviewing panel. You can find further details here: https://www.jobs.ac.uk/job/DNO177/research-assistant-associate-in-computational-neurology

A number of positions are open to applications until the 8th of August: https://www.circadianmedicine.de/ These include: • Postdoctoral Position – Circadian Neuroimmunology, Sleep and Alzheimer’s Disease (Project C02) at Charité – Universitätsmedizin Berlin, Campus Mitte (CCM) • Postdoctoral Position – Bioinformatics / Genomics (Project S01) at Charité – Universitätsmedizin Berlin, Campus Mitte (CCM) • Postdoctoral Position – Bioinformatics / Computational Biology (Project INF) at Charité – Universitätsmedizin Berlin, Campus Virchow-Klinikum (CVK) • PhD Position – Digital Interventions for Circadian Health and Mental Wellbeing (Project C03) at Charité – Universitätsmedizin Berlin, Campus Mitte (CCM) • PhD Position – Circadian Rhythms of Glucocorticoid and Glutamatergic Interactions in Mood Stability (Project C05) at University of Lübeck • PhD Position - Plasma Proteomics and Circadian Epidemiology (Project S01) at Charité – Universitätsmedizin Berlin, Campus Mitte (CCM) • PhD Position - Circadian Regulation of UV-Induced Autoimmunity in Lupus (Project A02) at University of Lübeck • PhD Position – Pneumonia and Circadian Rhythms (Project A03) at Charité – Universitätsmedizin Berlin, Campus Mitte (CCM) • PhD Position – Circadian Medicine: Connecting Rhythms and Immune Function at Single-Cell Resolution (Project A04) at Charité – Universitätsmedizin Berlin, Campus Mitte (CCM) • PhD Position – Circadian Medicine: Connecting Rhythms and Immune Function at Single-Cell Resolution (Project A04) at Charité – Universitätsmedizin Berlin, Campus Mitte (CCM) • PhD Position – Circadian Rhythms and Chronotherapy in Multiple Sclerosis (Project B01) at German Institute of Human Nutrition Potsdam-Rehbruecke and Charité – Universitätsmedizin Berlin, Campus Berlin Buch • PhD Position – Circadian Desynchronization and Epigenetic Crosstalk in Metabolic Steatohepatitis (Project B02) at Ludwig Maximillians University Munich • PhD Position – Chronotype, Puberty, and Metabolic Health in Adolescents (Project B03) at Charité – Universitätsmedizin Berlin, Campus Virchow Klinikum (CVK) • PhD Position – Chronotherapy of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) (Project B04) at University of Lübeck

Braintime Lab, Taipei Medical University (Taiwan)   The Braintime Lab is seeking a postdoctoral researcher for a three-year project, renewable annually, at the intersection of developmental and systems neuroscience within a circadian framework. Our work explores how circadian systems regulate cerebrospinal fluid dynamics and the neural network of the suprachiasmatic nucleus, combining mouse imaging and physiology with computational modeling.   Applicants should hold (or expect to complete by the start date) a PhD in neuroscience, biology, or a related field, have experience with rodent experiments, and preferably a background in circadian biology. Prior expertise in computational methods is not required, but a willingness to learn computational approaches is strongly encouraged.   The position offers a competitive salary, comprehensive benefits, and an international research environment. Postdoctoral fellows receive an annual round-trip flight home and may qualify for additional performance-based awards. For further information or to apply, please contact jihwan@tmu.edu.tw. We welcome international candidates; English is the working language, and discussions can also be conducted in Japanese or Korean if preferred.

Project Title: Applying animal opsins as optogenetic tools to understand the circadian clock Deadline for Application: 30/05/2025 Application details: https://www.findaphd.com/phds/project/erc-funded-applying-animal-opsins-as-optogenetic-tools-to-understand-the-circadian-clock/?p184165 About the Project The technique of optogenetics has revolutionised neuroscience by allowing the firing rate of targeted neurons to be remotely controlled by light. We are now working on providing a similar revolution to the most widespread targets of approved pharmaceuticals – G-protein signalling cascades. The opsin proteins that animals use to see are naturally light-activated G-protein coupled receptors and we are working with colleagues in Berlin and Switzerland on a major collaborative effort funded by the European Research Council to develop animal opsins as optogenetic tools to allow photic control of cells in the brain and throughout the body for experimental and therapeutic purposes. The successful candidate will join our group in Manchester applying the techniques of genetic engineering, cell and tissue culture, viral gene delivery and electrophysiological recordings to develop optimised variants of animal opsins, validate them in cell culture before applying them in vivo in laboratory mice. They will be expected to work productively not only with the local team in Manchester but with our collaborators in Germany and Switzerland.

The Seminar Series "Current Topics in Visual & Circadian Neuroscience" is organised by the Translational Sensory & Circadian Neuroscience Unit (MPS/TUM/TUMCREATE) led by Prof. Dr. Manuel Spitschan. The 60-minute (45 min. talk + 15 min. Q&A/discussion) graduate-level seminars are free to join and take place via Zoom.   Register now!   Speakers:   Monday, 28 April 2025 17:00 CEST | Achim Kramer (Charité – Universitätsmedizin Berlin) Monday, 5 May 2025 17:00 CEST | Takuma Morimoto (University of Oxford) Monday, 12 May 2025 17:00 CEST | William Tuten (University of California, Berkeley) Monday, 19 May 2025 17:00 CEST | Lisa Ostrin (University of Houston) Monday, 2 June 2025 10:00 CEST | Pauline Kang (UNSW Sydney) Monday, 16 June 2025 17:00 CEST | Annegret Dahlmann-Noor (Moorfields Eye Hospital & UCL) Monday, 23 June 2025 10:00 CEST | Raymond Najjar (National University of Singapore) Monday, 7 July 2025 17:00 CEST | Catherine Manning (University of Birmingham) Monday, 14 July 2025 17:00 CEST | Kyriaki Papantoniou (Medical University of Vienna)   Time zone conversion (for 1700 CEST): 0800 PDT | 1100 EDT | 1600 BST | 1700 CEST | 2300 SGT | 0000 JST | 0100 AEST

With the theme “Daylight Matters – Turning Knowledge into Change”, this year’s DLA Annual Conference aims to explore how scientific knowledge about daylight can be translated into meaningful action. Together, participants will identify key messages, target audiences, and effective communication activities to address knowledge-action gaps. Where is there a lack of evidence? Where do we already have sufficient knowledge, but it fails to reach the right audiences or drive change? Join us in developing strategies for integrating daylight into practices that benefit humans and nature. The role of transdisciplinary research in bridging disciplines and involving stakeholders will remain a central theme.  The conference will take place on 22-23 May 2025 at the Institute for Advanced Study of the Technical University of Munich (TUM-IAS) and will also be co-hosted by TUM. For more details, see the Daylight Academy Website: https://daylight.academy/events/annual-conference/

The Society for Light, Rhythms and Circadian Health (previously the The Society for Light Treatment and Biological Rhythms) are holding their 36th Annual Meeting from the 13th of June to the 16th of June. The most recent program (as of 03.04.2025) is attached and further details are available on the official website: https://slrch.org/

This upcoming course will be delivered at the University of Basel, it integrates topics covering the biological effects of daylight from various fields such as architecture, chronobiology, lighting design, medicine and psychology. This opens up theoretical and, above all, practical applications for improving public health. To find out more, see the official website: https://ihcdp.org/certificate-of-advanced-studies-cas-in-light-and-chronobiology/ Or contact the coordinator: Nadja Schaubhut, MSc, Course Coordinator nadja.schaubhut@unibas.ch, e-mail subject: CAS

A number of PhD Studentships and ECR Fellowships are available in Manchester, the home of the Centre for Biological Timing. ECR Fellowship Applications are already open: https://www.bmh.manchester.ac.uk/research/support/fellowships/bicentenary-early-career-research-fellowships/ And PhD Studentship Applications will open later this year: https://www.bmh.manchester.ac.uk/study/research/funding-fees/funded-programmes/bicentenary-studentships/ For further details see the links above and attachment below.

Closing Date & Time :14-Mar-2025 12:00 We are seeking a neuroscientist with a strong background in visual and/or circadian biology to work as part of the Sleep and Circadian Neuroscience Institute (SCNi) within the Nuffield Department of Clinical Neurosciences (NDCN). The research interests of the SCNi are to: (A) Understand the neural mechanisms that generate and regulate sleep and circadian biology (B) Define the mechanistic links between sleep/circadian rhythm disruption and disorders of the central nervous system and © Apply this knowledge for the development of evidence-based clinical interventions.   The successful candidate will be responsible for leading a specific research project entitled ‘Investigating the multiple roles of cryptochromes in animal magnetoreception’ which will be based within the SCNi. They will work closely with Prof Stuart Peirson ( https://www.ndcn.ox.ac.uk/team/stuart-peirson) and Mark Hankins ( https://www.ndcn.ox.ac.uk/team/mark-hankins).  This project is part of a Wellcome Discovery Award, in collaboration with the University of Leicester (Profs Ezio Rosato, Bambos Kyriacou), Manchester (Prof Richard Baines) and the National Physics Laboratory (Dr Alex Jones). Full details and application here.

For further details and application: https://www.findaphd.com/phds/project/understanding-the-role-of-the-vascular-clock-in-diabetic-retinopathy/?p180841 The deadline is on the 4th of March 2025. Objectives: 1. To investigate the role of the vascular clock in EC survival during early-stage DR using diabetic rodent models and human retinal endothelial cells (HRECs). 2. To evaluate whether the circadian clock regulates blood-retina barrier integrity and vessel permeability in vivo using STZ-induced diabetic mice and in vitro using HRECs. 3. To investigate how circadian rhythms affect leukocyte adhesion and infiltration in DR. The role of adhesion molecules in endothelial-leukocyte interactions will be examined both in vivo and in vitro. 4. To explore the role of the vascular clock in pathological angiogenesis such as occurring in proliferative diabetic retinopathy (PDR) using the oxygen-induced retinopathy (OIR) model, and in vitro assays to study vessel formation and neovascularization. The PhD student will work alongside two postdoctoral researchers and an animal technician within the Wellcome-Wolfson Institute for Experimental Medicine (WWIEM), in a collaborative environment with focus on vascular and vision research. This collaborative environment, shared resources, and expertise in diabetic retinopathy will ensure the success of the project. This project could offer new therapeutic strategies to target the vascular clock, potentially leading to better treatments for both early and advanced stages of DR. The results will be published in peer-reviewed journals and presented at conferences, contributing significantly to our understanding of endothelial circadian rhythms in diabetic vascular diseases.

Deadline: 15/05/2025 Details in document attached and applications below: PhD in genomics and proteomics technologies for advancing plant systems biology Postdoc in developing new long-read DNA sequence analysis workflows to study plant transposable elements (Bioinformatics, molecular biology) Postdoc in developing & applying new interactomics technologies in plant systems

The BioClock Consortium is a powerhouse of chronobiological research based in the Netherlands. Their Academy Series presents seminars with world-leading academic on a regular basis, all for free. See what's on the schedule in the coming months or catch up on what you missed: https://bioclockconsortium.org/en/academy-lectures/

We have a 3-Year postdoctoral and a research assistant position available to join our team, investigating how light and circadian mechanisms interact in the brain’s supraoptic nucleus to regulate daily rhythms and timing in the sleep and wake cycles. You will be joining the vibrant Division of Neuroscience and Centre for Biological Timing here in Manchester!   PDRA: https://www.jobs.manchester.ac.uk/Job/JobDetail?JobId=31512 Deadline: 27/02/2025 RA: https://www.jobs.manchester.ac.uk/Job/JobDetail?isPreview=Yes&jobid=31505&advert=external Deadline: 20/02/2025   Please get in touch if you are interested and want to hear more (mino.belle@manchester.ac.uk) OR pass on to anyone who might be interested.

Circadian Mental Health Network Conference 2025 5th-6th June 2025 Nucleus Building, University of Edinburgh We are excited to also announce two keynote speakers for the conference: Professor Anna Wirz-Justice and Dr Nicholas Meyer. This is a free event, and registration is open here: https://www.circadianmentalhealth.org/event-details-registration/circadian-mental-health-network-conference-2025 The full program is coming soon, but you can look forward to sessions on lived experience involvement in research, open data and the latest insights into current research.

Applications are now open for ESRS funding opportunities. These grants are designed to support the professional development of ESRS members while fostering collaboration and advancing knowledge in sleep research and sleep medicine. This is an excellent opportunity to contribute to the growth of our field. I encourage all eligible members to consider applying and take advantage of this initiative. 🔗 Learn more and apply here: https://esrs.eu/grants-awards/

Chronobiological changes in behaviour, development and immunity of salmon lice larvae (ChronoLice) Deadline for applications: 3rd February 2025, 10:00 GMT Project Description: The exciting PhD research project will help us understand the biology of sea lice (Lepeophtheirus salmonis), a pervasive and damaging fish parasite that causes substantial animal welfare, environmental and economic damage by impacting aquaculture of salmon. These copepod “lice” feed on fish mucus, skin and blood, causing lesions that allow secondary infections, reducing fish health and welfare. Control of lice has been focussed on the adult stages when attached to fish, but little is known about the biology of the free-swimming stages, which must locate and attached to a host to complete their life cycle. The project will address this fundamental knowledge gap by examining the parasite’s chronobiology, host seeking behaviour and physiological responses before and during attachment, and whether these can be disrupted or harnessed for reducing infestation. For more information on the project, see the attached document. You can apply via the FoodBioSystems DTP Page

ECR Central has compiled a database of active fellowships that enable researchers from various fields to work all around the world - see if there is something perfect for you! Access the database here: https://ecrcentral.org/fundings

Deadline: 10 Feb 2025 Apply here: https://www.imperial.ac.uk/jobs/search-jobs/description/index.php?nPostingId=15296&nPostingTargetId=22523&id=PMMFK026203F3VBQB8NLOV4CQ&LG=UK&languageSelect=UK&mask=ext Project: Leveraging circadian clocks to prevent Alzheimer’s disease In this project, you will develop new molecular tools modifying circadian pathways to prevent/ delay Alzheimer’s disease. This project stems from newly established mouse models and clock molecular targets identified in the Brancaccio Lab. You will perform viral delivery of gene therapy viral vectors, behavioural assessment of sleep-wake cycles and cognition, multiplexed live imaging in brain tissue, combinatorial intersectional genetics, and multivariate statistical analysis of time series to validate new chronotherapeutic interventions in Alzheimer’s disease. Further experience with analyses of large ‘OMICS dataset and advanced molecular biology tools in addition to stereotaxic brain surgery and live imaging will be an element of significant strength for this position. Previous knowledge of circadian biology is desirable but not strictly necessary. What we are looking for • You will be a motivated and organised researcher, excited by the science we do. • You will hold (or be near completion of) a PhD in neuroscience (or related discipline). • Experience of one or more laboratory techniques including live imaging microscopy and advanced techniques of molecular biology (e.g., cloning, viral vector design, construction and production, CRISPR/Cas9 and/or RNAi functional interference • Experience of one or more software packages is essential: MATLAB, ImageJ, SigmaPlot, • Prism, R, as is experience in statistical analysis. • Practical experience with RNAseq, RNA scope, and spatial transcriptomic techniques is highly desirable. • Experience with multivariate statistical analysis of (circadian) time series is highly desirable. What we can offer you This role is part of the UK Dementia Research Institute at Imperial College London, located in the Department of Brain Sciences.  You will benefit from an active research (and social) environment in the Department of Brain Sciences, with additional research labs in the Sir Michael Uren Hub on the nearby White City Campus. Postdocs in the UK DRI at Imperial enjoy excellent career development opportunities with: • Access to a range of cutting-edge technologies, i.e., real-time live imaging for circadian gene expression and neuronal and glial metabolic function, automated behavioural testing, single cell/nuclei transcriptomics, Imaging Mass Cytometry and computational modelling. • An inclusive and collegial working environment. • Strong national links through the UK DRI with attendance at its annual scientific meeting ‘Connectome’. • The opportunity to continue your career at a world-leading institution and be part of our mission to continue science for humanity. • Grow your career: Gain access to Imperial’s sector-leading dedicated career support for researchers as well as opportunities for promotion and progression • Sector-leading salary and remuneration package (including 39 days off a year and generous pension schemes). This role is offered on a full time, fixed term basis for 12 months, and is based at Hammersmith Campus. Please note, Candidates who have not yet been officially awarded their PhD will be appointed as Research Assistant.