I am a physiologist and clinical academic, specialising in veterinary neurology and neurosurgery. My research focuses on brain temperature and neural circadian rhythms. Human brain temperature varies spatiotemporally. This demands a reappraisal of how daily neuronal activity is regulated and raises questions about how brain-injured patients are managed. I want to understand how changes in brain temperature variability might predict and influence the manifestation of chronic brain disorders. Circadian and sleep disruption are increasingly associated with these disorders, but the impact of temperature variation on the neural clockwork and brain health is largely unexplored. I aim to address some of the prevailing controversies in neural chronobiology from a thermal, biophysical, and neurovascular perspective. My goal is to transform the therapeutic landscape for brain disease by understanding how brain clocks work, and how the brain works around the clock.

Humans; Non-human mammals excluding rodents; Mice or other rodents; Suprachiasmatic nucleus (SCN); Ex vivo system (other than SCN, derived from humans or other animals); Eukaryotic cells (including primary and transformed cell lines); Stem cells and stem cell-derived platforms; Synthetic; In silico, AI-driven, or theoretical